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Muscular Strength Gains - As a former power lifter, I thought a mile run was long distance and every now and then I would run to the gym and try to lift only to be burned out and unable to hit many of my previous high weight reps.  Cardio activity burns a lot of calories fast. In fact, you can burn up to 300-500 calories in half and hour if you are really pushing it.  As well, your glycogen stores can be lowered significantly and your body will try to make more glycogen out of fat, muscle, and remaining sugar in the body.  If you like to do cardio first, that is fine.  You can get used to it, but it usually requires rest periods and some sort of sugar / electrolyte replacement drink to help you through the workout.   Proper nutrition prior to working out cardio first / resistance second is a must too.  In fact, you should combine protein rich foods and carbs like fruit to give you the energy needed to get through the workouts.  Better yet - just lift first if you want to be strong and supplement your lifting with some cardio workouts for overall health and fat metabolizing.

 Overall Health - An overall health goal will consist of fat reduction, lean muscle mass gains, and cardio vascular function.  So, you need to do both aerobic activity like walking or running and anaerobic activity like weight lifting and calisthenics.  For optimal health results, you should mimic fat reduction method of resistance first / cardio second.  Many studies have shown that increased cardio function, fat loss, and lean muscle gains can be accomplished by lifting first then running.  In fact, improved cholesterol blood counts can be gained by cardiovascular first and resistance second.  You can see much of these health improvements by doing cardio or resistance ONLY, but to OPTIMIZE your health performance and improve / prevent illnesses such as diabetes, hypertension, hyperlipidemia, and other illnesses.  PS - if you smoke, you should stop. Smoking does not help at all with overall health gains.  Like I needed to tell you that.